Online Particle Size Analysis by DLS to Control Homogenizer Pressure
Online Particle Size Analysis by DLS to Control Homogenizer Pressure This customer was creating an emulsion in a precursor step to manufacture nanoparticles for drug delivery. The control of a high pressure homogenizer was critical to generate uniform droplet size at close to exactly 100 nm. Laboratory measurements did not give feedback quickly enough to…
Read MoreTiming the Replacement of Filters for CMP Slurry Processing
Timing the Replacement of Filters for CMP Slurry Processing The customer installed the AccuSizer Mini online particle size analyzer utilizing the FX sensor downstream of the filter in the supply line. The Figure below shows large particle count (LPC) data in particles/mL > 1.0 µm as a function of time. Once the AccuSizer Mini was…
Read MoreAccuSizer Autosampler Solves High Throughput Requirements
AccuSizer Autosampler Solves High Throughput Requirements Customers from several industries with different sample types have successfully implemented the PSS Autosampler to automate particle size and count measurements of up to 40 samples/hour. Successful customer examples include: Integrated with the AccuSizer SIS for high throughput USP <788> analysis of parenteral drugs Integrated with the AccuSizer APS…
Read MoreAccuSizer Replaces Laser Diffraction
AccuSizer Replaces Laser Diffraction A customer purchased a Nicomp and AccuSizer SIS to cover the broadest range of samples possible. A supplier used a laser diffraction method to define the particle size distribution of a powder. The customer wanted to confirm the incoming PSD using the AccuSizer SIS. Just dropping the powder into water –…
Read MoreNew Introduction to the Nicomp Video
Click here to watch a short introduction to the Nicomp DLS system. This video includes showing how a zeta potential measurement is made using the dip cell.
Read MoreApril Newsletter
April Newsletter The April 2015 PSS AccuSizer and Nicomp news included the following topics: Invitation to Nicomp DLS webinar New technical document: Why Buy a Nicomp New application note on liposomes New web page: Introduction to the AccuSizer New article on protein aggregation Read the complete newsletter
Read MoreMarch 2015 Newsletter
March Newsletter The March 2015 PSS AccuSizer and Nicomp news included the following topics: Invitation to SPOS webinar New technical support documents; Nicomp system verification and AccuSizer count standards procedures New application note on CMP filter efficiency New web pages: Online DLS systems and 2015 trade shows Read the complete newsletter.
Read MoreDocument Download Center
Visit the new Document Download Center to automatically download documents including: Brochures Application Note Technical Notes Just fill in your name, company, location, and email address and you can then download any of the available material.
Read MoreOctober Newsletter
October Newsletter Highlight: Using Online DLS to Monitor Production of Nanoparticles for Drug Delivery Online Monitoring of Nanoparticles for Drug Delivery Research into nanoparticles for drug delivery is now turning into products on the market. The particle size distribution is a critical physical property that influences quality and yield. Most companies…
Read MoreProtein Aggregation
Aggregation in protein solution based therapeutics can have deleterious effects such as inducing a response from the immune system. Measurement of these aggregates has been possible for larger aggregates, but smaller aggregates in the range of 0.150 nm to 2 microns have been difficult to quantify. Dynamic Light Scattering (DLS) techniques can demonstrate the existence…
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