Case Study

Online Particle Size Analysis by DLS to Control Homogenizer Pressure

Online Particle Size Analysis by DLS to Control Homogenizer Pressure This customer was creating an emulsion in a precursor step to manufacture nanoparticles for drug delivery. The control of a high pressure homogenizer was critical to generate uniform droplet size at close to exactly 100 nm. Laboratory measurements did not give feedback quickly enough to…

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Timing the Replacement of Filters for CMP Slurry Processing

Timing the Replacement of Filters for CMP Slurry Processing The customer installed the AccuSizer Mini online particle size analyzer utilizing the FX sensor downstream of the filter in the supply line. The Figure below shows large particle count (LPC) data in particles/mL > 1.0 µm as a function of time. Once the AccuSizer Mini was…

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AccuSizer Autosampler Solves High Throughput Requirements

AccuSizer Autosampler Solves High Throughput Requirements Customers from several industries with different sample types have successfully implemented the PSS Autosampler to automate particle size and count measurements of up to 40 samples/hour. Successful customer examples include: Integrated with the AccuSizer SIS for high throughput USP <788> analysis of parenteral drugs Integrated with the AccuSizer APS…

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AccuSizer Replaces Laser Diffraction

AccuSizer Replaces Laser Diffraction A customer purchased a Nicomp and AccuSizer SIS to cover the broadest range of samples possible. A supplier used a laser diffraction method to define the particle size distribution of a powder. The customer wanted to confirm the incoming PSD using the AccuSizer SIS. Just dropping the powder into water –…

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