Online Particle Size Analysis by DLS to Control Homogenizer Pressure

Online Particle Size Analysis by DLS to Control Homogenizer Pressure This customer was creating an emulsion in a precursor step to manufacture nanoparticles for drug delivery. The control of a high pressure homogenizer was critical to generate uniform droplet size at close to exactly 100 nm. Laboratory measurements did not give feedback quickly enough to…

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Timing the Replacement of Filters for CMP Slurry Processing

Timing the Replacement of Filters for CMP Slurry Processing The customer installed the AccuSizer Mini online particle size analyzer utilizing the FX sensor downstream of the filter in the supply line. The Figure below shows large particle count (LPC) data in particles/mL > 1.0 µm as a function of time. Once the AccuSizer Mini was…

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AccuSizer Autosampler Solves High Throughput Requirements

AccuSizer Autosampler Solves High Throughput Requirements Customers from several industries with different sample types have successfully implemented the PSS Autosampler to automate particle size and count measurements of up to 40 samples/hour. Successful customer examples include: Integrated with the AccuSizer SIS for high throughput USP <788> analysis of parenteral drugs Integrated with the AccuSizer APS…

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AccuSizer Replaces Laser Diffraction

AccuSizer Replaces Laser Diffraction A customer purchased a Nicomp and AccuSizer SIS to cover the broadest range of samples possible. A supplier used a laser diffraction method to define the particle size distribution of a powder. The customer wanted to confirm the incoming PSD using the AccuSizer SIS. Just dropping the powder into water –…

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April Newsletter

 April Newsletter The April 2015 PSS AccuSizer and Nicomp news included the following topics:  Invitation to Nicomp DLS webinar New technical document: Why Buy a Nicomp New application note on liposomes New web page: Introduction to the AccuSizer New article on protein aggregation Read the complete newsletter

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March 2015 Newsletter

March Newsletter The March 2015 PSS AccuSizer and Nicomp news included the following topics:  Invitation to SPOS webinar New technical support documents; Nicomp system verification and AccuSizer count standards procedures New application note on CMP filter efficiency New web pages: Online DLS systems and 2015 trade shows Read the complete newsletter.    

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Document Download Center

Visit the new Document Download Center to automatically download documents including:     Brochures Application Note Technical Notes Just fill in your name, company, location, and email address and you can then download any of the available material.

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October Newsletter

October Newsletter Highlight: Using Online DLS to Monitor Production of Nanoparticles for Drug Delivery Online Monitoring of Nanoparticles for Drug Delivery         Research into nanoparticles for drug delivery is now turning into products on the market. The particle size distribution is a critical physical property that influences quality and yield. Most companies…

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Protein Aggregation

Aggregation in protein solution based therapeutics can have deleterious effects such as inducing a response from the immune system.  Measurement of these aggregates has been possible for larger aggregates, but smaller aggregates in the range of 0.150 nm to 2 microns have been difficult to quantify.  Dynamic Light Scattering (DLS) techniques can demonstrate the existence…

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