Subvisible Particles Detection in Parenteral Drugs
Parenteral drugs are delivered into the body by directly injecting into the intravenous, subcutaneous, or intramuscular routes. Subvisible particle counting in parenteral drugs is described in USP <788>, a common application for the AccuSizer SIS system. The same system can also be used for USP <789> for ophthalmic solutions and the new USP <787> test for therapeutic protein injections.
The USP <729> test for globule size distribution in lipid injectable emulsions calls for systems like the AccuSizer APS for Method II and the Nicomp DLS system for Method I.
Click the image above to watch a presentation on using the PSS AccuSizer to count and size particulate matter in parenteral drugs.
Read the sections below for additional information on these applications.